Periodontal ligament stem cells regulate apoptosis of neutrophils
نویسندگان
چکیده
منابع مشابه
Periodontal Ligament Stem Cells Regulate Apoptosis of Neutrophils
Periodontal ligament stem cells (PDLSCs) are promising cell resource for the cell-based therapy for periodontitis and regeneration of bio-root. In this study, we investigated the effect of PDLSCs on neutrophil, a critical constituent of innate immunity, and the underlying mechanisms. The effect of PDLSCs on the proliferation and apoptosis of resting neutrophils and IL-8 activated neutrophils wa...
متن کاملPeriodontal Ligament Stem Cells
Millions of people experience consequential tooth loss related to irretrievable damage of the periodontium caused by deep caries, severe periodontal diseases or irreversible trauma, resulting in a decreased quality of life. Hence, dental scientists have focused much attention on tissue engineering techniques in an effort to address this condition. The periodontium is composed mainly of two soft...
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Objective(s): The aim of this study was to investigate the effect of curcumin on the osteogenic differentiation of human periodontal ligament stem cells (hPDLSCs) and its underlying potential mechanism.Materials and Methods: The tissue explant adherence method was used to isolate hPDLSCs. Flowcytometry, Alizarin Red staining and Oil Red ...
متن کاملPeriodontal Ligament Stem Cells - a Review
It is astonishing how quickly the field of genetics has progressed in the past 50 years since the structure of the DNA molecule was first reported. Another major discovery that may revolutionize health care practices has been the derivation of human embryonic stem cells. These cells can be coaxed into developing specific tissues or organs to replace ones that have been lost to disease. The iden...
متن کاملThe potential of human-derived periodontal ligament stem cells to osteogenic differentiation: An In vitro investigation
Background: Periodontal ligament stem cells (PDLSCs) are considered as a type of mesenchymal stem cell that is beneficial target for numerous clinical applications in periodontal tissue regeneration therapy. Materials and Methods: This study examined the effects of dexamethasone (Dex) on human PDLSCs in vitro. PDLSCs obtained from the roots of patient’s teeth were cultured with Dex (0....
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ژورنال
عنوان ژورنال: Open Medicine
سال: 2017
ISSN: 2391-5463
DOI: 10.1515/med-2017-0004